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pentobarbital will lessen the level or outcome of cinacalcet by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.pentobarbital will lessen the level or effect of cobimetinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Keep away from coadministration. Solid or reasonable CYP3A inducers